Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14520624 | 0.83 | — | — | |
| SCHEMBL21038290 | 0.83 | CYP2C19 (0.52) | CYP2C19RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL6682630 | 0.83 | — | — | |
| SCHEMBL22295329 | 0.83 | CYP2C19 (0.52) | CYP2C19RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL625666 | 0.83 | — | — | |
| SCHEMBL19832281 | 0.80 | CYP2C19 (0.53) | CYP2C19RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL91135 | 0.79 | — | — | |
| SCHEMBL30444415 | 0.79 | CYP2C19 (0.61) | CYP2C19RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL10390855 | 0.79 | — | — | |
| SCHEMBL4202449 | 0.76 | CYP2C19 (0.53) | CYP2C19RAB9AKMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842420-B1 | HETEROARYL INHIBITORS OF PDE4 | TETRA DISCOVERY PARTNERS LLC (US) | 2022-12-07 | — | — | EP | disclosed |