Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947585 | 1.00 | HSD17B10 (0.57) | HSD17B10LRRK2PIK3CDDYRK1AMAP3K5 | |
| SCHEMBL24729270 | 0.89 | HSD17B10 (0.61) | HSD17B10LRRK2DYRK1AMAP3K5KDM4E | |
| SCHEMBL29947498 | 0.89 | HSD17B10 (0.61) | HSD17B10LRRK2DYRK1AMAP3K5KDM4E | |
| SCHEMBL29947647 | 0.88 | PIK3CD (0.50) | HSD17B10PIK3CDDYRK1AKDM4ENPC1 | |
| SCHEMBL24729325 | 0.88 | PIK3CD (0.50) | HSD17B10PIK3CDDYRK1AKDM4ENPC1 | |
| SCHEMBL24729230 | 0.87 | MAP3K5 (0.65) | HSD17B10LRRK2PIK3CDDYRK1AMAP3K5 | |
| SCHEMBL24729322 | 0.85 | HSD17B10 (0.60) | HSD17B10LRRK2KDM4ENPC1ALDH1A1 | |
| SCHEMBL24729375 | 0.85 | HSD17B10 (0.57) | HSD17B10LRRK2DYRK1AMAP3K5KDM4E | |
| SCHEMBL24729506 | 0.85 | HSD17B10 (0.63) | HSD17B10LRRK2DYRK1AMAP3K5CSNK1D | |
| SCHEMBL29947347 | 0.85 | HSD17B10 (0.57) | HSD17B10LRRK2DYRK1AMAP3K5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | disclosed |