Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 8/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.66 |
| ▸ | NPC1 | O15118 | 6/20 | 0.66 |
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | MITF | O75030 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.66 |
| ▸ | RELA | Q04206 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947574 | 1.00 | TP53 (0.66) | TP53SMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL24729389 | 0.87 | TP53 (0.62) | TP53SMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL29947586 | 0.87 | TP53 (0.62) | TP53SMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL29947618 | 0.85 | TP53 (0.60) | TP53SMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL24729365 | 0.85 | TP53 (0.60) | TP53SMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL24729352 | 0.85 | NPC1 (0.71) | TP53SMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL29947690 | 0.85 | NPC1 (0.71) | TP53SMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL24729562 | 0.84 | TP53 (0.59) | TP53SMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL29947609 | 0.84 | TP53 (0.59) | TP53SMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL24729260 | 0.84 | SMN1; SMN2 (0.78) | TP53SMN1; SMN2NPC1RAB9AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | disclosed |