Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 14/20 | 0.83 |
| ▸ | NPC1 | O15118 | 6/20 | 0.76 |
| ▸ | RAB9A | P51151 | 6/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.76 |
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | DHODH | Q02127 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947567 | 1.00 | SCD (0.83) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL31065 | 0.91 | SCD (1.00) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16742048 | 0.88 | SCD (0.85) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL13561185 | 0.87 | SCD (0.83) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL3405017 | 0.87 | SCD (0.83) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4916511 | 0.86 | NPC1 (1.00) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16554145 | 0.86 | SCD (0.88) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4912951 | 0.85 | SCD (1.00) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL29947616 | 0.84 | KDM4E (0.75) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL24729350 | 0.84 | KDM4E (0.75) | SCDNPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | disclosed |