Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2478995 | 0.91 | HDAC1 (0.51) | HDAC1UTS2RHDAC3HDAC2MEN1 | |
| SCHEMBL2474402 | 0.87 | UTS2R (0.47) | HDAC1UTS2RHDAC3HDAC2NCOR2 | |
| SCHEMBL3832675 | 0.86 | UTS2R (0.56) | HDAC1UTS2RHDAC3HDAC2NCOR2 | |
| SCHEMBL3832758 | 0.83 | UTS2R (0.49) | HDAC1UTS2RHDAC3HDAC2NCOR2 | |
| SCHEMBL2476829 | 0.82 | UTS2R (0.49) | HDAC1UTS2RHDAC3HDAC2MEN1 | |
| SCHEMBL2471256 | 0.81 | UTS2R (0.58) | HDAC1UTS2RHDAC3HDAC2NCOR2 | |
| SCHEMBL2474421 | 0.81 | HDAC1 (0.48) | HDAC1UTS2RHDAC3HDAC2NPC1 | |
| SCHEMBL2478630 | 0.81 | HDAC1 (0.56) | HDAC1UTS2RHDAC3HDAC2NCOR2 | |
| SCHEMBL2473027 | 0.80 | HDAC1 (0.52) | HDAC1HDAC3HDAC2NPC1RAB9A | |
| SCHEMBL2474066 | 0.80 | HDAC1 (0.62) | HDAC1UTS2RHDAC3HDAC2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-B1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2011-10-12 | — | — | EP | claimed |