⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19157965 | 0.78 | — | — | |
| SCHEMBL22309117 | 0.78 | SOS1 (0.31) | — | |
| SCHEMBL19342127 | 0.73 | SOS1 (0.31) | — | |
| SCHEMBL20731912 | 0.72 | — | — | |
| SCHEMBL25165189 | 0.70 | — | — | |
| SCHEMBL14660767 | 0.70 | — | — | |
| SCHEMBL23180503 | 0.70 | — | — | |
| SCHEMBL20965588 | 0.68 | SOS1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL31691938 | 0.68 | SOS1 (0.59) | — | |
| Hydrochloric Acid SCHEMBL14660860 | 0.68 | SOS1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | VALO HEALTH, INC. (US) | 2022-12-13 | — | — | US | disclosed |