Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22615432 | 0.88 | ADORA1 (0.42) | NR1H2POLBHTTATMESR2 | |
| SCHEMBL1174623 | 0.86 | NR1H2 (0.50) | NR1H2POLBHTTATMESR2 | |
| SCHEMBL31368516 | 0.84 | NR1H2 (0.45) | NR1H2POLBHTTATMESR2 | |
| SCHEMBL24732108 | 0.83 | NR1H2 (0.42) | NR1H2POLBHTTATMESR2 | |
| SCHEMBL22165552 | 0.82 | HTT (0.43) | NR1H2POLBHTTATMESR2 | |
| SCHEMBL17926078 | 0.82 | NR1H2 (0.41) | NR1H2POLBHTTATMESR2 | |
| SCHEMBL1175786 | 0.81 | MEN1 (0.41) | NR1H2ESR2GPR119ADORA1MAPT | |
| SCHEMBL22143168 | 0.80 | MAPT (0.40) | NR1H2POLBHTTATMESR2 | |
| SCHEMBL12255700 | 0.80 | NR1H2 (0.40) | NR1H2POLBHTTATMESR2 | |
| SCHEMBL12255693 | 0.80 | POLB (0.42) | NR1H2POLBHTTATMESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022247770-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海璎黎药业有限公司 | 2022-12-01 | — | — | WO | disclosed |