SCHEMBL2473259

SCHEMBL2473259

CN(C)CCCC(NC(=O)NC(C)(C)C)c1ccc(C(=O)Nc2ccccc2N)cc1

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 7/20 0.51
HDAC1 Q13547 11/20 0.48
HDAC3 O15379 5/20 0.45
HDAC2 Q92769 5/20 0.45
NCOR2 Q9Y618 4/20 0.45
PTGS1 P23219 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3832758 0.85 UTS2R (0.49) UTS2RHDAC1HDAC3HDAC2NCOR2
SCHEMBL2478630 0.85 HDAC1 (0.56) UTS2RHDAC1HDAC3HDAC2NCOR2
SCHEMBL2474066 0.84 HDAC1 (0.62) UTS2RHDAC1HDAC3HDAC2NCOR2
SCHEMBL2470960 0.84 UTS2R (0.46) UTS2RHDAC1HDAC3HDAC2NCOR2
SCHEMBL3831092 0.83 UTS2R (0.48) UTS2RHDAC1HDAC3HDAC2NCOR2
SCHEMBL3837712 0.83 UTS2R (0.48) UTS2RHDAC1HDAC3HDAC2NCOR2
SCHEMBL2472961 0.83 HDAC1 (0.55) UTS2RHDAC1HDAC3HDAC2NCOR2
SCHEMBL2474421 0.83 HDAC1 (0.48) UTS2RHDAC1HDAC3HDAC2NCOR2
SCHEMBL2476829 0.83 UTS2R (0.49) UTS2RHDAC1HDAC3HDAC2NCOR2
SCHEMBL2474402 0.83 UTS2R (0.47) UTS2RHDAC1HDAC3HDAC2NCOR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2107052-B1 NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE SANTEN PHARMACEUTICAL CO LTD (JP) 2011-10-12 EP claimed