Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30779219 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53PKMKDM4EMEN1 | |
| SCHEMBL24732842 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL24732810 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2TP53PKMMEN1KMT2A | |
| SCHEMBL24733060 | 0.80 | TLR7 (0.40) | SMN1; SMN2TP53PKMKDM4EALDH1A1 | |
| SCHEMBL29809070 | 0.80 | TLR7 (0.40) | SMN1; SMN2TP53PKMKDM4EALDH1A1 | |
| SCHEMBL28802625 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2TP53PKMMEN1KMT2A | |
| SCHEMBL27213601 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53PKMMEN1KMT2A | |
| SCHEMBL27213627 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2TP53PKMKDM4EMEN1 | |
| SCHEMBL28802609 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2TP53PKMMEN1KMT2A | |
| SCHEMBL28802603 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53KDM4EMAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736210-A | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| WO-2022161420-A1 | CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |