Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24732834 | 0.92 | TLR7 (0.54) | TLR7TLR8 | |
| SCHEMBL24732839 | 0.90 | TLR7 (0.57) | TLR7TLR8 | |
| SCHEMBL24732743 | 0.90 | TLR7 (0.52) | TLR7TLR8 | |
| SCHEMBL29809003 | 0.90 | TLR7 (0.57) | TLR7TLR8 | |
| SCHEMBL24732582 | 0.90 | TLR7 (0.57) | TLR7TLR8 | |
| SCHEMBL24732906 | 0.89 | TLR7 (0.56) | TLR7TLR8 | |
| SCHEMBL24733519 | 0.89 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL24732848 | 0.89 | TLR7 (0.56) | TLR7TLR8 | |
| SCHEMBL24732830 | 0.89 | TLR7 (0.52) | TLR7TLR8 | |
| SCHEMBL24732711 | 0.89 | TLR7 (0.51) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161420-A1 | CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |