SCHEMBL24734656

SCHEMBL24734656

CN1CCCC(O)(CO)CC1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.33
RBP1 P09455 1/20 0.32
EHMT2 Q96KQ7 1/20 0.31
KMT2A Q03164 1/20 0.31
CHKA P35790 1/20 0.30
GAA P10253 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3436780 0.91 NPSR1 (0.33) NPSR1RBP1KMT2AGAAMAPK1
Hydrochloric Acid SCHEMBL28233292 0.89 NPSR1 (0.32) NPSR1RBP1GAAMAPK1
SCHEMBL24837477 0.83 USP2 (0.36) NPSR1EHMT2
SCHEMBL20007916 0.81 KMT2A (0.33) NPSR1KMT2AGAA
SCHEMBL17888369 0.78 NPSR1 (0.31) NPSR1
SCHEMBL17888395 0.78 SMN1; SMN2 (0.40) NPSR1KMT2A
SCHEMBL16564680 0.77
SCHEMBL3478088 0.75 KDM4E (0.41) RBP1KMT2AGAA
SCHEMBL17888210 0.75 KMT2A (0.37) KMT2A
SCHEMBL19063296 0.74 EPHX1 (0.34) NPSR1EHMT2KMT2ACHKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023196720-A2 LRRK2 INHIBITORS Brenig Therapeutics, Inc. (US) 2023-10-12 WO disclosed
WO-2022261210-A1 KRAS MODULATORS AND USES THEREOF QUANTA THERAPEUTICS, INC. (US) 2022-12-15 WO disclosed
WO-2022256459-A1 KRAS MODULATORS AND USES THEREOF QUANTA THERAPEUTICS, INC. (US) 2022-12-08 WO disclosed