⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24735051 | 0.87 | — | — | |
| SCHEMBL22062797 | 0.79 | — | — | |
| SCHEMBL21340210 | 0.77 | — | — | |
| SCHEMBL24735053 | 0.77 | — | — | |
| SCHEMBL21340400 | 0.77 | — | — | |
| SCHEMBL12749919 | 0.77 | — | — | |
| SCHEMBL21340013 | 0.77 | — | — | |
| SCHEMBL25533075 | 0.77 | — | — | |
| SCHEMBL24966316 | 0.76 | — | — | |
| SCHEMBL25533579 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530222-B2 | Substituted pyrrolopyrimidine and pyrazolopyrimidine as Bruton's tyrosine kinase (BTK) degraders | ACCUTAR BIOTECHNOLOGY INC. (US) | 2022-12-20 | — | — | US | disclosed |