Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.73 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27766437 | 1.00 | TSHR (1.00) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| SCHEMBL15900 | 1.00 | TSHR (1.00) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| SCHEMBL5014268 | 1.00 | TSHR (1.00) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| Iodide SCHEMBL6672021 | 0.97 | TSHR (0.94) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| Trimethylammonium SCHEMBL8195424 | 0.97 | TSHR (0.94) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| Hydrochloric Acid SCHEMBL8743641 | 0.97 | TSHR (0.94) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| Bromide SCHEMBL414532 | 0.97 | TSHR (0.94) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| Hydrochloric Acid SCHEMBL6391891 | 0.97 | TSHR (0.94) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| SCHEMBL7911439 | 0.97 | TSHR (0.94) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| Ammonia Solution, Strong SCHEMBL25238492 | 0.97 | TSHR (0.94) | TSHRALDH1A1TAAR1AOC3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530210-B2 | Substituted heteroaromatic pyrazolo-pyridines and their use as GLUN2B receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11530210-B2 | Substituted heteroaromatic pyrazolo-pyridines and their use as GLUN2B receptor modulators | GRIN2B, GRIN2A, GRIN2C | TSHR 766/4885ALDH1A1 2477/4885TAAR1 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.