Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.52 |
| ▸ | AR | P10275 | 7/20 | 0.48 |
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29841370 | 1.00 | CRBN (0.58) | CRBNDDB1ARHPGDS | |
| SCHEMBL24671137 | 0.88 | CRBN (0.62) | CRBNDDB1ARHPGDS | |
| SCHEMBL30068320 | 0.88 | CRBN (0.62) | CRBNDDB1ARHPGDS | |
| SCHEMBL24735582 | 0.87 | CRBN (0.65) | CRBNDDB1ARHPGDS | |
| SCHEMBL29841305 | 0.87 | CRBN (0.65) | CRBNDDB1ARHPGDS | |
| SCHEMBL26928955 | 0.87 | CRBN (0.60) | CRBNDDB1AR | |
| SCHEMBL30693000 | 0.87 | CRBN (0.60) | CRBNDDB1AR | |
| SCHEMBL27462922 | 0.86 | CRBN (0.59) | CRBNDDB1ARHPGDS | |
| SCHEMBL30692990 | 0.86 | CRBN (0.56) | CRBNDDB1AR | |
| SCHEMBL26928967 | 0.86 | CRBN (0.56) | CRBNDDB1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530222-B2 | Substituted pyrrolopyrimidine and pyrazolopyrimidine as Bruton's tyrosine kinase (BTK) degraders | ACCUTAR BIOTECHNOLOGY INC. (US) | 2022-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11530222-B2 | Substituted pyrrolopyrimidine and pyrazolopyrimidine as Bruton's tyrosine kinase (BTK) degraders | BTK, LYN, SYK | CRBN 692/4885DDB1 1446/4885AR 4702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.