⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18085982 | 0.83 | — | — | |
| SCHEMBL9910016 | 0.73 | — | — | |
| SCHEMBL12741070 | 0.69 | SOS1 (0.31) | — | |
| SCHEMBL17694855 | 0.68 | — | — | |
| SCHEMBL12741065 | 0.67 | — | — | |
| SCHEMBL14749867 | 0.62 | — | — | |
| SCHEMBL21690259 | 0.61 | — | — | |
| SCHEMBL14592861 | 0.61 | TSHR (0.31) | — | |
| SCHEMBL19276649 | 0.61 | — | — | |
| SCHEMBL25456272 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387395-A1 | UREA, AMIDE, AND SUBSTITUTED HETEROARYL COMPOUNDS FOR CBL-B INHIBITION | NURIX THERAPEUTICS, INC. | 2022-12-08 | — | — | US | disclosed |