SCHEMBL24736835

SCHEMBL24736835

CCNC1(CO)CCOCC1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.42
OPRL1 P41146 1/20 0.34
RAF1 P04049 1/20 0.33
BRAF P15056 1/20 0.33
CD274 Q9NZQ7 1/20 0.32
HTT P42858 1/20 0.31
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21843932 0.88 DPP4 (0.34) DPP4EPHX1
SCHEMBL25082838 0.84
SCHEMBL7902872 0.79 DPP4 (0.38) DPP4
SCHEMBL8950833 0.79
SCHEMBL13674443 0.78 HTT (0.31) HTT
SCHEMBL7118954 0.78 DPP4 (0.39) DPP4OPRL1RAF1BRAFCD274
SCHEMBL420729 0.77 DPP4 (0.37) DPP4OPRL1RAF1BRAFEPHX1
SCHEMBL20403033 0.77
Hydrochloric Acid SCHEMBL16268608 0.74 TSHR (0.39) DPP4
SCHEMBL24004510 0.72 DPP4 (0.35) DPP4OPRL1RAF1BRAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3759085-B1 SUBSTITUTED CYCLOHEXYL COMPOUNDS AS NOP INHIBITORS DART NEUROSCIENCE LLC (US) 2022-12-14 EP disclosed