SCHEMBL24739062

CC(C)(C)O[C@H]1C[C@@H](COCC(=O)N2CCN(c3ncc(C(F)(F)F)cn3)CC2)N(c2cc(C(F)(F)F)c(=O)[nH]n2)C1

nearest known ligand 0.59

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	TIPARP	Q7Z3E1	20/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24739172	0.91	TIPARP (0.71)	TIPARP
SCHEMBL24739068	0.88	TIPARP (0.57)	TIPARP
SCHEMBL24739177	0.88	TIPARP (0.57)	TIPARP
SCHEMBL24738978	0.84	TIPARP (0.79)	TIPARP
SCHEMBL24739414	0.84	TIPARP (0.79)	TIPARP
SCHEMBL24739454	0.83	TIPARP (0.73)	TIPARP
SCHEMBL24739452	0.83	TIPARP (0.73)	TIPARP
SCHEMBL24739286	0.82	TIPARP (0.62)	TIPARP
SCHEMBL24739122	0.82	TIPARP (0.71)	TIPARP
SCHEMBL24739296	0.82	TIPARP (0.71)	TIPARP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022253101-A1	PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR	上海优理惠生医药有限公司	2022-12-08	—	—	WO	disclosed