SCHEMBL24739458

SCHEMBL24739458

O=C(CC[C@H]1CCCN1c1cc(C(F)(F)F)c(=O)[nH]n1)N1CCN(c2ncc(C(F)(F)F)cn2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TIPARP Q7Z3E1 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25272747 1.00 TIPARP (1.00) TIPARP
SCHEMBL24739049 1.00 TIPARP (1.00) TIPARP
SCHEMBL25261104 0.97 TIPARP (1.00) TIPARP
SCHEMBL25261107 0.97 TIPARP (1.00) TIPARP
SCHEMBL24739375 0.97 TIPARP (1.00) TIPARP
SCHEMBL25697204 0.93 TIPARP (0.86) TIPARP
SCHEMBL24738980 0.92 TIPARP (0.84) TIPARP
SCHEMBL25697591 0.91 TIPARP (0.83) TIPARP
SCHEMBL25697902 0.90 TIPARP (0.86) TIPARP
SCHEMBL25697899 0.90 TIPARP (0.86) TIPARP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022253101-A1 PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR 上海优理惠生医药有限公司 2022-12-08 WO disclosed