SCHEMBL24744147

SCHEMBL24744147

CC1(C)c2ccccc2-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc4c(c3)-c3c(-c5ccc6ccccc6c5)ccc5cccc(c35)C4(C)C)cc21

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24744159 0.97 PDK2 (0.31) HDAC4HDAC2HDAC8
SCHEMBL24744605 0.96 PDK2 (0.31)
SCHEMBL24744600 0.96 PDK2 (0.32)
SCHEMBL24744139 0.96 HDAC4 (0.33) HDAC4HDAC2HDAC8
SCHEMBL24744145 0.95 ADORA2A (0.32) ADORA2AADORA1
SCHEMBL24744146 0.95 ADORA2A (0.32) ADORA2AADORA1
SCHEMBL24744257 0.95 PDK2 (0.30)
SCHEMBL24744254 0.95 PDK2 (0.30)
SCHEMBL24744569 0.93 PDK2 (0.32) HDAC4HDAC2HDAC8
SCHEMBL24744136 0.93 GSTP1 (0.32) HDAC4HDAC2HDAC8ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022260240-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2022-12-15 WO disclosed