Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474434 | 1.00 | MAOB (0.57) | MAOBALDH1A1LMNAPOLBHTT | |
| SCHEMBL2474429 | 1.00 | MAOB (0.57) | MAOBALDH1A1LMNAPOLBHTT | |
| SCHEMBL2477144 | 0.85 | MAOB (0.64) | MAOBALDH1A1POLBHTTMAPT | |
| SCHEMBL2477140 | 0.85 | MAOB (0.64) | MAOBALDH1A1POLBHTTMAPT | |
| SCHEMBL2477147 | 0.85 | MAOB (0.64) | MAOBALDH1A1POLBHTTMAPT | |
| SCHEMBL2477506 | 0.83 | MAOB (0.53) | MAOBLMNAGAATSHRMAPK1 | |
| SCHEMBL2477504 | 0.83 | MAOB (0.53) | MAOBLMNAGAATSHRMAPK1 | |
| SCHEMBL2477505 | 0.83 | MAOB (0.53) | MAOBLMNAGAATSHRMAPK1 | |
| SCHEMBL18995691 | 0.74 | KMT2A (0.46) | ALDH1A1LMNAPOLBHTTMAPT | |
| SCHEMBL12171018 | 0.74 | MAOB (0.77) | MAOBALDH1A1TSHRMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217549-A2 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING, AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-08-18 | — | — | EP | claimed |
| WO-2009052970-A2 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING, AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-04-30 | — | — | WO | claimed |
| EP-2388245-B1 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PIRAMAL IMAGING SA (CH) | 2017-07-12 | — | — | EP | disclosed |
| EP-2374779-A1 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | Bayer Pharma Aktiengesellschaft (DE) | 2011-10-12 | — | — | EP | disclosed |