Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 18/20 | 0.61 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.61 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | IL1B | P01584 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30121822 | 1.00 | DDB1 (0.61) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL31090662 | 1.00 | DDB1 (0.61) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL31090622 | 1.00 | DDB1 (0.61) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL31090626 | 1.00 | DDB1 (0.61) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL24744845 | 1.00 | DDB1 (0.61) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL24744848 | 1.00 | DDB1 (0.61) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL24746778 | 1.00 | DDB1 (0.61) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL24744852 | 1.00 | DDB1 (0.61) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL31090564 | 1.00 | DDB1 (0.61) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL29262086 | 1.00 | DDB1 (0.61) | DDB1CRBNIKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253713-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |