Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.66 |
| ▸ | CA2 | P00918 | 2/20 | 0.66 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.60 |
| ▸ | STAT3 | P40763 | 5/20 | 0.57 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.52 |
| ▸ | PDE6D | O43924 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30000878 | 1.00 | CRBN (0.66) | CRBNCA2DDB1STAT3DYRK2 | |
| SCHEMBL29986813 | 0.97 | CRBN (0.64) | CRBNCA2DDB1STAT3HDAC3 | |
| SCHEMBL25204590 | 0.97 | CRBN (0.64) | CRBNCA2DDB1STAT3HDAC3 | |
| SCHEMBL29877119 | 0.97 | CRBN (0.61) | CRBNCA2DDB1STAT3DYRK2 | |
| SCHEMBL30000661 | 0.96 | CRBN (0.63) | CRBNCA2DDB1STAT3DYRK2 | |
| SCHEMBL25237183 | 0.94 | CRBN (0.62) | CRBNCA2DDB1STAT3HDAC3 | |
| SCHEMBL29986699 | 0.94 | CRBN (0.62) | CRBNCA2DDB1STAT3HDAC3 | |
| SCHEMBL19475853 | 0.92 | STAT3 (0.64) | CRBNCA2DDB1STAT3DYRK2 | |
| SCHEMBL19475706 | 0.92 | STAT3 (0.64) | CRBNCA2DDB1STAT3DYRK2 | |
| SCHEMBL19508773 | 0.92 | STAT3 (0.64) | CRBNCA2DDB1STAT3DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253713-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |