Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 10/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469865 | 0.89 | SCD (0.54) | SCD | |
| SCHEMBL2474664 | 0.89 | SCD (0.54) | SCDCHRM2CHRM1 | |
| SCHEMBL2468437 | 0.88 | SCD (0.55) | SCDCHRM2CHRM1 | |
| SCHEMBL2468449 | 0.88 | SCD (0.55) | SCD | |
| SCHEMBL1600528 | 0.85 | SCD (0.71) | SCD | |
| SCHEMBL2470065 | 0.84 | SCD (0.73) | SCD | |
| SCHEMBL2466615 | 0.84 | SCD (0.49) | SCD | |
| SCHEMBL2473461 | 0.83 | SCD (0.62) | SCD | |
| SCHEMBL15190370 | 0.83 | SCD (0.51) | SCDALDH1A1GAANPSR1 | |
| SCHEMBL2469867 | 0.82 | SCD (0.50) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648874-B1 | PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2011-10-05 | — | — | EP | claimed |