Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16690791 | 0.84 | MAPK1 (0.41) | BRD4MAPK1 | |
| SCHEMBL16690790 | 0.84 | TNKS (0.41) | BRD4TNKSMAPK1 | |
| SCHEMBL23108841 | 0.82 | MAPK1 (0.40) | BRD4MAPK1TLR8TLR7 | |
| SCHEMBL23133583 | 0.82 | BRD4 (0.38) | BRD4MAPK1 | |
| SCHEMBL23102773 | 0.82 | BRD4 (0.38) | BRD4MAPK1PDE4APDE4BPDE4C | |
| SCHEMBL23102761 | 0.82 | MAPK1 (0.40) | BRD4MAPK1TLR8TLR7 | |
| SCHEMBL25147361 | 0.82 | BRD4 (0.38) | BRD4MAPK1PDE4APDE4BPDE4C | |
| SCHEMBL23425724 | 0.82 | BRD4 (0.38) | BRD4MAPK1PDE4APDE4BPDE4C | |
| SCHEMBL23102775 | 0.82 | MAPK1 (0.40) | BRD4MAPK1TLR8TLR7 | |
| SCHEMBL15448420 | 0.80 | BRD4 (0.50) | BRD4PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |