SCHEMBL2474693

SCHEMBL2474693

Nn1c(-c2ccccn2)nnc1-c1ccccn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 1.00
TP53 P04637 4/20 1.00
SMN1; SMN2 Q16637 3/20 1.00
TSHR P16473 1/20 1.00
RAB9A P51151 5/20 0.59
L3MBTL1 Q9Y468 10/20 0.55
KDM4E B2RXH2 5/20 0.54
LMNA P02545 4/20 0.54
CCR1 P32246 2/20 0.54
CCR5 P51681 2/20 0.54
CCR8 P51685 2/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
METAP1 P53582 1/20 0.54
BLM P54132 1/20 0.54
HIF1A Q16665 1/20 0.54
DOHH Q9BU89 1/20 0.54
P4HTM Q9NXG6 1/20 0.54
MAPT P10636 2/20 0.54
ATM Q13315 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30242943 1.00 NPC1 (1.00) NPC1TP53SMN1; SMN2TSHRRAB9A
SCHEMBL3990726 0.87 NPC1 (0.76) NPC1TP53SMN1; SMN2TSHRRAB9A
SCHEMBL13984199 0.82 NPC1 (0.69) NPC1TP53SMN1; SMN2TSHRRAB9A
SCHEMBL24832607 0.76 NPC1 (0.61) NPC1TP53SMN1; SMN2TSHRRAB9A
Dipyridyl SCHEMBL6885910 0.75 KDM4E (0.93) NPC1TP53SMN1; SMN2TSHRRAB9A
Dipyridyl SCHEMBL8655605 0.75 KDM4E (0.93) NPC1TP53SMN1; SMN2TSHRRAB9A
SCHEMBL14465345 0.75 NPC1 (0.60) NPC1TP53SMN1; SMN2TSHRRAB9A
Dipyridyl SCHEMBL3711450 0.72 KDM4E (1.00) NPC1TP53SMN1; SMN2TSHRRAB9A
Dipyridyl SCHEMBL29907716 0.72 KDM4E (1.00) NPC1TP53SMN1; SMN2TSHRRAB9A
Dipyridyl SCHEMBL29351528 0.72 KDM4E (1.00) NPC1TP53SMN1; SMN2TSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109265484-B Metal iridium-triazole crystal-graphene oxide ternary nonlinear optical material and preparation method thereof 江苏大学 2021-02-12 CN claimed
EP-2158620-B1 PIEZOCHROME COMPOSITE TOTALFOERSVARETS FORSKNINGSINS (SE) 2011-10-12 EP claimed
US-20100188727-A1 PIEZOCHROME COMPOSITE TOTALFORSVARETS FORSKNINGSINSTITUT (SE) 2010-07-29 US claimed
EP-2158620-A1 PIEZOCHROME COMPOSITE Totalförsvarets Forskningsinstitut (SE) 2010-03-03 EP claimed
EP-2014797-A2 Coating composition for interconnection part of electrode and plasma display panel including the same Samsung SDI Co., Ltd. (KR) 2009-01-14 EP claimed
US-20080303439-A1 Coating composition for interconnection part of electrode and plasma display panel including the same SAMSUNG SDI CO., LTD., A CORP. OF THE REPUBLIC OF KOREA (KR) 2008-12-11 US claimed
WO-2008147282-A1 PIEZOCHROME COMPOSITE Totalförsvarets Forskningsinstitut (SE) 2008-12-04 WO claimed
EP-0667562-B1 Charge injection barrier for positive charging organic photoconductor HEWLETT PACKARD CO (US) 2001-03-21 EP claimed
US-5380458-A Bleach COLGATE-PALMOLIVE CO. (US) 1995-01-10 US claimed
EP-0615543-A1 STABILIZED HYPOHALITE COMPOSITIONS Colgate-Palmolive Company (US) 1994-09-21 EP claimed
WO-1994007987-A1 STABILIZED HYPOHALITE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 1994-04-14 WO claimed
EP-4692940-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, ELECTRONIC DEVICE, AND ELECTRONIC DEVICE MANUFACTURING METHOD Sumitomo Bakelite Co., Ltd. (JP) 2026-02-11 EP disclosed
CN-115873149-A Perfluoro sulfonic acid ionic polymer with triazole group, proton membrane and membrane electrode for fuel cell and preparation method thereof 山东东岳未来氢能材料股份有限公司 2023-03-31 CN disclosed
CN-115698855-A Photosensitive resin composition 住友电木株式会社 2023-02-03 CN disclosed
CN-110914756-B Photosensitive resin composition, resin film, and electronic device 住友电木株式会社 2021-05-04 CN disclosed
US-5442060-A Treating hyperlipemia, atherosclerosis MITSUBISHI KASEI CORPORATION (JP) 1995-08-15 US disclosed
US-5380458-A Bleach COLGATE-PALMOLIVE CO. (US) 1995-01-10 US disclosed
EP-0615543-A1 STABILIZED HYPOHALITE COMPOSITIONS Colgate-Palmolive Company (US) 1994-09-21 EP disclosed
WO-1994007987-A1 STABILIZED HYPOHALITE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 1994-04-14 WO disclosed
EP-0591830-A1 Carboxamide and urea derivatives having ACAT-inhibiting activityM Mitsubishi Chemical Corporation (JP) 1994-04-13 EP disclosed