SCHEMBL2474776

SCHEMBL2474776

Cc1ccc(NC(=O)Oc2ccc(N3CCN(C(=O)c4ccccc4C(F)(F)F)CC3)nn2)cc1C

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SCD O00767 13/20 0.56
DCTPP1 Q9H773 2/20 0.50
NPY2R P49146 1/20 0.49
GBA1 P04062 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2469803 0.93 SCD (0.59) SCDDCTPP1NPY2R
SCHEMBL2468520 0.93 SCD (0.58) SCDDCTPP1NPY2R
SCHEMBL2470081 0.91 SCD (0.61) SCDDCTPP1
SCHEMBL2463407 0.90 SCD (0.59) SCDDCTPP1GBA1
SCHEMBL2473906 0.90 SCD (0.58) SCDDCTPP1GBA1
SCHEMBL2470144 0.89 SCD (0.62) SCDDCTPP1NPY2R
SCHEMBL2465053 0.89 SCD (0.59) SCDDCTPP1
SCHEMBL2469795 0.89 SCD (0.71) SCDDCTPP1
SCHEMBL2467138 0.88 SCD (0.54) SCDDCTPP1GBA1
SCHEMBL2465401 0.88 SCD (0.62) SCDDCTPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1648874-B1 PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC (CA) 2011-10-05 EP claimed