SCHEMBL24749320

SCHEMBL24749320

O=C1CN(c2c(O)cc(-c3cc(F)cc(F)c3)cc2F)S(=O)(=O)N1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 9/20 0.57
PTPN2 P17706 16/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25325524 0.90 PTPN1 (0.55) PTPN1PTPN2
SCHEMBL24747526 0.90 PTPN1 (0.55) PTPN1PTPN2
SCHEMBL24747513 0.89 PTPN1 (0.52) PTPN1PTPN2
SCHEMBL3128181 0.89 PTPN1 (0.61) PTPN1PTPN2
SCHEMBL24747730 0.85 PTPN1 (0.53) PTPN1PTPN2
SCHEMBL25325422 0.85 PTPN1 (0.53) PTPN1PTPN2
SCHEMBL25326383 0.84 PTPN1 (0.52) PTPN1PTPN2
SCHEMBL25326295 0.83 PTPN1 (0.51) PTPN1PTPN2
SCHEMBL30529952 0.83 PTPN1 (0.51) PTPN1PTPN2
SCHEMBL24750712 0.83 PTPN1 (0.53) PTPN1PTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022261145-A1 COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES NESS THERAPEUTICS, INC. (US) 2022-12-15 WO disclosed