Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.47 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25990369 | 0.81 | MCL1 (0.47) | MCL1ACACBHSD17B10HTTALDH1A1 | |
| SCHEMBL8015155 | 0.74 | — | — | |
| SCHEMBL6212435 | 0.72 | MCL1 (0.54) | MCL1ACACBHSD17B10HTTALDH1A1 | |
| SCHEMBL6321739 | 0.72 | MCL1 (0.54) | MCL1ACACBHSD17B10HTTALDH1A1 | |
| SCHEMBL1896933 | 0.71 | — | — | |
| SCHEMBL24200201 | 0.71 | — | — | |
| SCHEMBL6317467 | 0.71 | MCL1 (0.52) | MCL1ACACBHSD17B10ALDH1A1GAA | |
| SCHEMBL10428329 | 0.70 | MCL1 (0.47) | MCL1ACACBHSD17B10HTTALDH1A1 | |
| SCHEMBL12919551 | 0.70 | — | — | |
| SCHEMBL23696762 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022242743-A1 | HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-11-24 | — | — | WO | disclosed |