Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28675651 | 0.85 | HPGD (0.50) | LMNAHPGDCES2GALR3CYP1A2 | |
| SCHEMBL23116951 | 0.81 | CA12 (0.42) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL24754328 | 0.79 | HPGD (0.56) | HPGDCES2GALR3CYP1A2CYP2C9 | |
| SCHEMBL2313707 | 0.79 | CA12 (0.70) | LMNAHPGDCES2GALR3CYP1A2 | |
| SCHEMBL31083917 | 0.79 | CA12 (0.70) | LMNAHPGDCES2GALR3CYP1A2 | |
| SCHEMBL25372530 | 0.78 | HPGD (0.49) | LMNAHPGDCES2GALR3CYP1A2 | |
| SCHEMBL23116725 | 0.78 | POLB (0.51) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL3527659 | 0.77 | CA12 (0.46) | LMNAHPGDCA12CA1CA2 | |
| SCHEMBL23115286 | 0.77 | CA12 (0.62) | LMNAHPGDCES2CA12CA1 | |
| SCHEMBL23714898 | 0.75 | MIF (0.47) | LMNAHPGDALOX15KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262782-A1 | GLUTARIMIDE-SUBSTITUTED ISOXAZOLE FUSED RING COMPOUND, AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2022-12-22 | — | — | WO | disclosed |