Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 12/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24754295 | 0.93 | DDB1 (0.48) | DDB1CRBNCA12CA1CA9 | |
| SCHEMBL26159194 | 0.83 | CRBN (0.41) | DDB1CRBNHTR1FHTR1A | |
| SCHEMBL24950362 | 0.82 | CA12 (0.44) | DDB1CRBNCA12CA1CA9 | |
| SCHEMBL23116931 | 0.80 | PTPRC (0.41) | DDB1CRBNHTR1FHTR1A | |
| SCHEMBL26158807 | 0.80 | DDB1 (0.43) | DDB1CRBN | |
| SCHEMBL24754291 | 0.79 | DDB1 (0.42) | DDB1CRBN | |
| SCHEMBL29324610 | 0.79 | DDB1 (0.44) | DDB1CRBN | |
| SCHEMBL24949587 | 0.79 | DDB1 (0.47) | DDB1CRBNHTR1FHTR1A | |
| SCHEMBL24939755 | 0.79 | DDB1 (0.45) | DDB1CRBNHTR1ABRD4CREBBP | |
| SCHEMBL30661576 | 0.79 | DDB1 (0.72) | DDB1CRBNCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262782-A1 | GLUTARIMIDE-SUBSTITUTED ISOXAZOLE FUSED RING COMPOUND, AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2022-12-22 | — | — | WO | disclosed |