SCHEMBL24754865

SCHEMBL24754865

CCOC(=O)[C@H](CCc1nc2cc(N(CCCl)CCCl)ccc2n1C)NC(=O)[C@@H](N)Cc1ccc(F)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC6 Q9UBN7 4/20 0.49
▸ HDAC1 Q13547 3/20 0.49
▸ HDAC3 O15379 2/20 0.49
▸ HDAC4 P56524 2/20 0.49
▸ HDAC2 Q92769 2/20 0.49
▸ HDAC8 Q9BY41 2/20 0.49
▸ HDAC5 Q9UQL6 2/20 0.49
▸ PTGS1 P23219 2/20 0.49
▸ HDAC10 Q969S8 1/20 0.49
▸ SMN1; SMN2 Q16637 4/20 0.38
▸ KMT2A Q03164 4/20 0.38
▸ CYP3A4 P08684 3/20 0.38
▸ LMNA P02545 3/20 0.38
▸ MEN1 O00255 3/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ ALOX15 P16050 2/20 0.38
▸ HIF1A Q16665 2/20 0.38
▸ ABCB11 O95342 1/20 0.38
▸ CHRM2 P08172 1/20 0.38
▸ ADRA2A P08913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29184592 1.00 HDAC6 (0.49) HDAC6HDAC1HDAC3HDAC4HDAC2
Hydrochloric Acid SCHEMBL29184729 0.99 HDAC6 (0.49) HDAC6HDAC1HDAC3HDAC4HDAC2
Hydrochloric Acid SCHEMBL30807123 0.99 HDAC6 (0.49) HDAC6HDAC1HDAC3HDAC4HDAC2
Hydrochloric Acid SCHEMBL29184730 0.99 HDAC6 (0.49) HDAC6HDAC1HDAC3HDAC4HDAC2
SCHEMBL24754848 0.95 HDAC1 (0.47) HDAC6HDAC1HDAC3HDAC4HDAC2
SCHEMBL24754752 0.95 HDAC1 (0.47) HDAC6HDAC1HDAC3HDAC4HDAC2
SCHEMBL24754637 0.95 HDAC6 (0.49) HDAC6HDAC1HDAC3HDAC4HDAC2
SCHEMBL27431735 0.95 HDAC6 (0.49) HDAC6HDAC1HDAC3HDAC4HDAC2
SCHEMBL24754620 0.95 HDAC6 (0.47) HDAC6HDAC1HDAC3HDAC4HDAC2
Hydrochloric Acid SCHEMBL29184704 0.94 HDAC1 (0.46) HDAC6HDAC1HDAC3HDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4633679-A1 PEPTIDE DRUG CONJUGATES Oncopeptides Innovation AB (SE) 2025-10-22 — — EP claimed
US-20240316059-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES AB (SE) 2024-09-26 — — US claimed
WO-2024126845-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES INNOVATION AB (SE) 2024-06-20 — — WO claimed
WO-2024121379-A1 NOVEL THERAPEUTIC COMBINATIONS ONCOPEPTIDES INNOVATION AB (SE) 2024-06-13 — — WO claimed
EP-4355370-A1 PEPTIDE DRUG CONJUGATES Oncopeptides Innovation AB (SE) 2024-04-24 — — EP claimed
CN-117794580-A Polypeptide coupling medicine 肿瘤多肽有限公司 2024-03-29 — — CN claimed
WO-2022263679-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES AB (SE) 2022-12-22 — — WO claimed
EP-4633679-A1 PEPTIDE DRUG CONJUGATES Oncopeptides Innovation AB (SE) 2025-10-22 — — EP disclosed
US-20240316059-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES AB (SE) 2024-09-26 — — US disclosed
WO-2024126845-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES INNOVATION AB (SE) 2024-06-20 — — WO disclosed
WO-2024121379-A1 NOVEL THERAPEUTIC COMBINATIONS ONCOPEPTIDES INNOVATION AB (SE) 2024-06-13 — — WO disclosed
WO-2024121379-A1 NOVEL THERAPEUTIC COMBINATIONS ONCOPEPTIDES INNOVATION AB (SE) 2024-06-13 — — WO disclosed
EP-4355370-A1 PEPTIDE DRUG CONJUGATES Oncopeptides Innovation AB (SE) 2024-04-24 — — EP disclosed
CN-117794580-A Polypeptide coupling medicine 肿瘤多肽有限公司 2024-03-29 — — CN disclosed
WO-2022263679-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES AB (SE) 2022-12-22 — — WO disclosed
WO-2022263679-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES AB (SE) 2022-12-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240316059-A1 PEPTIDE DRUG CONJUGATES MCL1, DNPEP, VIP HDAC6 627/4885HDAC1 2830/4885HDAC3 2573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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