SCHEMBL24755692

SCHEMBL24755692

CCOC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCc1nc2cc(N(CCCl)CCCl)ccc2n1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC3 O15379 2/20 0.46
▸ HDAC4 P56524 2/20 0.46
▸ HDAC1 Q13547 2/20 0.46
▸ HDAC2 Q92769 2/20 0.46
▸ HDAC8 Q9BY41 2/20 0.46
▸ HDAC6 Q9UBN7 2/20 0.46
▸ HDAC5 Q9UQL6 2/20 0.46
▸ PTGS1 P23219 1/20 0.46
▸ HDAC10 Q969S8 1/20 0.46
▸ NPY4R P50391 8/20 0.36
▸ NPY1R P25929 6/20 0.36
▸ IL1RN P18510 5/20 0.34
▸ ERAP2 Q6P179 5/20 0.34
▸ NPY2R P49146 5/20 0.33
▸ NPY5R Q15761 4/20 0.33
▸ ERAP1 Q9NZ08 4/20 0.33
▸ LMNA P02545 1/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29184614 0.99 HDAC3 (0.46) HDAC3HDAC4HDAC1HDAC2HDAC8
Hydrochloric Acid SCHEMBL29184611 0.99 HDAC3 (0.46) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL24754848 0.95 HDAC1 (0.47) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL24754752 0.95 HDAC1 (0.47) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL24754637 0.95 HDAC6 (0.49) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL27431735 0.95 HDAC6 (0.49) HDAC3HDAC4HDAC1HDAC2HDAC8
Hydrochloric Acid SCHEMBL29184677 0.95 HDAC1 (0.46) HDAC3HDAC4HDAC1HDAC2HDAC8
Hydrochloric Acid SCHEMBL29184704 0.95 HDAC1 (0.46) HDAC3HDAC4HDAC1HDAC2HDAC8
Hydrochloric Acid SCHEMBL30807136 0.95 HDAC1 (0.46) HDAC3HDAC4HDAC1HDAC2HDAC8
Hydrochloric Acid SCHEMBL29184675 0.95 HDAC1 (0.46) HDAC3HDAC4HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4633679-A1 PEPTIDE DRUG CONJUGATES Oncopeptides Innovation AB (SE) 2025-10-22 — — EP claimed
US-20240316059-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES AB (SE) 2024-09-26 — — US claimed
WO-2024126845-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES INNOVATION AB (SE) 2024-06-20 — — WO claimed
WO-2024121379-A1 NOVEL THERAPEUTIC COMBINATIONS ONCOPEPTIDES INNOVATION AB (SE) 2024-06-13 — — WO claimed
EP-4355370-A1 PEPTIDE DRUG CONJUGATES Oncopeptides Innovation AB (SE) 2024-04-24 — — EP claimed
WO-2022263679-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES AB (SE) 2022-12-22 — — WO claimed
EP-4633679-A1 PEPTIDE DRUG CONJUGATES Oncopeptides Innovation AB (SE) 2025-10-22 — — EP disclosed
US-20240316059-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES AB (SE) 2024-09-26 — — US disclosed
WO-2024126845-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES INNOVATION AB (SE) 2024-06-20 — — WO disclosed
WO-2024121379-A1 NOVEL THERAPEUTIC COMBINATIONS ONCOPEPTIDES INNOVATION AB (SE) 2024-06-13 — — WO disclosed
WO-2024121379-A1 NOVEL THERAPEUTIC COMBINATIONS ONCOPEPTIDES INNOVATION AB (SE) 2024-06-13 — — WO disclosed
EP-4355370-A1 PEPTIDE DRUG CONJUGATES Oncopeptides Innovation AB (SE) 2024-04-24 — — EP disclosed
WO-2022263679-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES AB (SE) 2022-12-22 — — WO disclosed
WO-2022263679-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES AB (SE) 2022-12-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240316059-A1 PEPTIDE DRUG CONJUGATES MCL1, DNPEP, VIP HDAC3 2573/4885HDAC4 1544/4885HDAC1 2830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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