Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20075947 | 0.89 | CRBN (0.47) | CRBNDDB1ALDH1A1LMNAHTT | |
| SCHEMBL22297292 | 0.89 | CRBN (0.47) | CRBNDDB1ALDH1A1LMNAHTT | |
| SCHEMBL20463181 | 0.88 | CRBN (0.41) | CRBNDDB1ESR1 | |
| SCHEMBL22520771 | 0.85 | DDB1 (0.54) | CRBNDDB1ALDH1A1LMNA | |
| SCHEMBL27370432 | 0.82 | CRBN (0.37) | CRBNDDB1ESR1 | |
| SCHEMBL24294674 | 0.82 | CRBN (0.45) | CRBNDDB1ALDH1A1 | |
| SCHEMBL20323937 | 0.82 | CRBN (0.45) | CRBNDDB1ALDH1A1 | |
| SCHEMBL23712164 | 0.82 | CRBN (0.47) | CRBNDDB1ALDH1A1LMNAHTT | |
| SCHEMBL22454336 | 0.82 | CRBN (0.39) | CRBNDDB1ALDH1A1 | |
| SCHEMBL25771919 | 0.81 | CRBN (0.46) | CRBNDDB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266206-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2022-12-22 | — | — | WO | disclosed |