Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24761197 | 0.89 | PRSS1 (0.43) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL3071986 | 0.88 | F13A1 (0.43) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL22546602 | 0.87 | F13A1 (0.42) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL11990731 | 0.87 | F13A1 (0.42) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL24760629 | 0.86 | PRSS1 (0.41) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL13130772 | 0.86 | F13A1 (0.41) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL13029063 | 0.86 | F13A1 (0.41) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL21706330 | 0.86 | F13A1 (0.41) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL24760578 | 0.85 | PRSS1 (0.44) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL24760586 | 0.85 | F13A1 (0.41) | PRSS1TPSAB1F13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262789-A1 | ANTITUMOR COMPOUND AND USE THEREOF | 明慧医药（杭州）有限公司 | 2022-12-22 | — | — | WO | disclosed |