Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 16/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972613 | 1.00 | LPAR1 (0.48) | LPAR1HSP90AA1MAPTHTTNPSR1 | |
| SCHEMBL2479468 | 0.89 | LPAR1 (0.50) | LPAR1HSP90AA1MAPTHTTNPSR1 | |
| SCHEMBL1014862 | 0.89 | LPAR1 (0.50) | LPAR1HSP90AA1MAPTHTTNPSR1 | |
| SCHEMBL972329 | 0.89 | LPAR1 (0.52) | LPAR1HSP90AA1MAPTHTTNPSR1 | |
| SCHEMBL6037763 | 0.89 | LPAR1 (0.52) | LPAR1HSP90AA1MAPTHTTNPSR1 | |
| SCHEMBL970994 | 0.89 | LPAR1 (0.52) | LPAR1HSP90AA1MAPTHTTNPSR1 | |
| SCHEMBL972615 | 0.83 | LPAR1 (0.46) | LPAR1LPAR2 | |
| SCHEMBL5573057 | 0.82 | LPAR1 (0.60) | LPAR1LPAR2 | |
| SCHEMBL5573045 | 0.82 | LPAR1 (0.60) | LPAR1LPAR2 | |
| SCHEMBL5573047 | 0.82 | LPAR1 (0.60) | LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695955-B1 | COMPOUNDS HAVING LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISM AND USES THEREOF | ONO PHARMACEUTICAL CO (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-1695955-A1 | COMPOUNDS HAVING LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISM AND USES THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-08-30 | — | — | EP | disclosed |