SCHEMBL247619

SCHEMBL247619

Nc1cc(Cl)cc(Cl)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29838724 1.00
SCHEMBL3661086 0.85
SCHEMBL190461 0.78
SCHEMBL13884662 0.78
SCHEMBL2185366 0.74
SCHEMBL16603063 0.74
SCHEMBL2034856 0.74
SCHEMBL17923127 0.74
SCHEMBL15542009 0.74
SCHEMBL17923105 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4225762-B1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMA (US) 2026-05-27 EP disclosed
US-12612416-B2 Modulators of cystic fibrosis transmembrane conductance regulator VERTEX PHARMACEUTICALS INCORPORATED (US) 2026-04-28 US disclosed
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 EP disclosed
EP-4694893-A1 NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME TME Therapeutics LLC (US) 2026-02-18 EP disclosed
EP-4694981-A1 HETEROCYCLIC COMPOUNDS AS DUAL INHIBITORS OF PD-L1 AND ADENOSINE RECEPTORS Aurigene Oncology Limited (IN) 2026-02-18 EP disclosed
EP-4688778-A1 1H-PYRROLO[2,3-B]PYRIDIN-4-YL]-2-OXOPYRROLIDINE-3-CARBONITRILE DERIVATIVES AS TYROSINE KINASE 2 (TYK2) INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES Biogen MA Inc. (US) 2026-02-11 EP disclosed
EP-4680607-A1 BICYCLIC UREAS AS KINASE INHIBITORS Incyte Corporation (US) 2026-01-21 EP disclosed
EP-4673441-A1 LZK INHIBITORS Ureka Bioscienes, Inc. (US) 2026-01-07 EP disclosed
US-20250388541-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-12-25 US disclosed
US-20250388543-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-12-25 US disclosed
US-7108724-B2 Anti-pilling treating method for protein fiber material OKAMOTO CORPORATION (JP) 2006-09-19 US disclosed
US-20040261189-A1 Anti-pilling treating method for protein fiber material OKAMOTO CORPORATION (JP) 2004-12-30 US disclosed
CN-1044075-C Chinese herbal medicine plant pesticide and preparation method thereof LI YING (CN) 1999-07-14 CN disclosed
EP-0590685-B1 Process for optical resolution of (+)-cis-4-aminocyclopent-2-en-1-carboxylic acid derivative KURARAY CO (JP) 1996-05-29 EP disclosed
EP-0329170-B1 Process for producing 2-amino-4,6-dichloropyrimidine ISHIHARA SANGYO KAISHA (JP) 1995-06-21 EP disclosed
US-5371282-A Process for optical resolution of (+)-cis-4-aminocyclopent-2-en-1-carboxylic acid derivative KURARAY CO., LTD. (JP) 1994-12-06 US disclosed
EP-0590685-A1 Process for optical resolution of (+)-cis-4-aminocyclopent-2-en-1-carboxylic acid derivative KURARAY CO., LTD. (JP) 1994-04-06 EP disclosed
CN-1077193-A N-5 position-protected 2,5-diamino-4,6-dichloro pyrimidine and production method thereof LONZA AG (CH) 1993-10-13 CN disclosed
US-4929729-A REACTION WITH PHOSPHOROUS OXYCHLORIDE, HYDROLYSIS, CHLORINATION ISHIHARA SANGYO KAISHA LTD. (JP) 1990-05-29 US disclosed
EP-0329170-A2 Process for producing 2-amino-4,6-dichloropyrimidine ISHIHARA SANGYO KAISHA, LTD. (JP) 1989-08-23 EP disclosed