SCHEMBL2476192

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2503488	0.91	TNK2 (0.56)	LCKSRCKDRMAPK14TNK2
	SCHEMBL2502950	0.91	LCK (0.59)	LCKSRCKDRMAPK14TNK2
	SCHEMBL2505157	0.89	TNK2 (0.54)	LCKSRCKDRMAPK14TNK2
	SCHEMBL2501179	0.89	TNK2 (0.54)	TNK2EGFRCSF1RWEE1KCNH2
	SCHEMBL12197654	0.88	TNK2 (0.54)	LCKSRCKDRMAPK14TNK2
	SCHEMBL2504855	0.87	WEE1 (0.63)	LCKSRCKDRMAPK14TNK2
	SCHEMBL2499907	0.87	TNK2 (0.54)	LCKSRCKDRMAPK14TNK2
	SCHEMBL2476657	0.86	TNK2 (0.55)	LCKSRCKDRMAPK14TNK2
	SCHEMBL2499591	0.86	TNK2 (0.54)	LCKSRCKDRMAPK14TNK2
	SCHEMBL2481378	0.86	SLC2A1 (0.57)	LCKSRCKDRMAPK14TNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.