Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 20/20 | 0.56 |
| ▸ | CRBN | Q96SW2 | 20/20 | 0.56 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23807960 | 0.96 | DDB1 (0.54) | DDB1CRBNIKZF3 | |
| SCHEMBL24764457 | 0.95 | DDB1 (0.57) | DDB1CRBNIKZF3 | |
| SCHEMBL21997960 | 0.92 | CRBN (0.54) | DDB1CRBN | |
| SCHEMBL21069913 | 0.89 | CRBN (0.60) | DDB1CRBNIKZF3 | |
| SCHEMBL21997891 | 0.89 | CRBN (0.53) | DDB1CRBN | |
| SCHEMBL23807961 | 0.89 | DDB1 (0.54) | DDB1CRBNIKZF3 | |
| SCHEMBL22526629 | 0.89 | CRBN (0.54) | DDB1CRBN | |
| SCHEMBL30169425 | 0.89 | CRBN (0.54) | DDB1CRBN | |
| SCHEMBL21997046 | 0.88 | CRBN (0.58) | DDB1CRBNIKZF3 | |
| SCHEMBL21070078 | 0.88 | CRBN (0.53) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220356185-A1 | MERTK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2022-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220356185-A1 | MERTK DEGRADERS AND USES THEREOF | MERTK, ITK, CRKL | DDB1 3837/4885CRBN 183/4885IKZF3 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.