Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30042705 | 1.00 | DDB1 (0.82) | DDB1CRBN | |
| SCHEMBL24764819 | 0.93 | DDB1 (0.71) | DDB1CRBN | |
| SCHEMBL30043350 | 0.93 | DDB1 (0.71) | DDB1CRBN | |
| SCHEMBL21069953 | 0.90 | DDB1 (0.84) | DDB1CRBN | |
| SCHEMBL31664181 | 0.90 | DDB1 (0.84) | DDB1CRBN | |
| SCHEMBL21070751 | 0.86 | DDB1 (0.81) | DDB1CRBN | |
| SCHEMBL30043012 | 0.84 | DDB1 (0.58) | DDB1CRBN | |
| SCHEMBL24765076 | 0.84 | DDB1 (0.58) | DDB1CRBN | |
| SCHEMBL21070759 | 0.83 | DDB1 (0.73) | DDB1CRBN | |
| SCHEMBL21069887 | 0.82 | DDB1 (1.00) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220356185-A1 | MERTK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2022-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220356185-A1 | MERTK DEGRADERS AND USES THEREOF | MERTK, ITK, CRKL | DDB1 3837/4885CRBN 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.