SCHEMBL24765686

SCHEMBL24765686

CC(C)N[C@@H](Cc1ccccc1)C(=O)NCCN1C(=O)C=CC1=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.66
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.45
OPRM1 P35372 1/20 0.44
OPRD1 P41143 1/20 0.44
OPRK1 P41145 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
GSK3A P49840 3/20 0.42
GSK3B P49841 3/20 0.42
MGLL Q99685 2/20 0.42
CTSS P25774 2/20 0.41
CTSK P43235 2/20 0.41
BCHE P06276 1/20 0.41
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
MMP1 P03956 1/20 0.40
MMP9 P14780 1/20 0.40
LAP3 P28838 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22915431 1.00 AKT1 (0.66) AKT1CYP3A4TSHROPRM1OPRD1
SCHEMBL22987322 0.88 AKT1 (0.69) AKT1CYP3A4TSHROPRM1OPRD1
SCHEMBL22915374 0.84 AKT1 (0.71) AKT1CYP3A4TSHROPRM1OPRD1
SCHEMBL22915399 0.84 AKT1 (0.71) AKT1CYP3A4TSHROPRM1OPRD1
SCHEMBL22987290 0.82 AKT1 (0.69) AKT1OPRM1OPRD1OPRK1L3MBTL1
SCHEMBL22915395 0.81 AKT1 (0.67) AKT1L3MBTL1CTSSCHRNB2CHRNB4
SCHEMBL22987323 0.81 AKT1 (0.66) AKT1OPRM1OPRD1OPRK1L3MBTL1
SCHEMBL18435144 0.80 KMT2A (0.56) CYP3A4TSHRCYP2D6CYP2C9CYP2C19
SCHEMBL18435286 0.80 KMT2A (0.56) CYP3A4TSHRCYP2D6CYP2C9CYP2C19
SCHEMBL22915477 0.80 AKT1 (1.00) AKT1CTSSCTSKCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11472892-B2 Reactive alginic acid derivatives MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2022-10-18 US disclosed