Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24119648 | 0.90 | HTR2A (0.61) | HTR2AALOX5PTGS2TAAR1HMGCR | |
| SCHEMBL17388702 | 0.83 | TAAR1 (0.45) | HTR2ATAAR1 | |
| SCHEMBL31035919 | 0.81 | TAAR1 (0.72) | HTR2ATAAR1 | |
| SCHEMBL19663956 | 0.80 | HTR2A (0.49) | HTR2AALOX5PTGS2TAAR1HMGCR | |
| SCHEMBL29151839 | 0.79 | HMGCR (0.65) | HTR2AALOX5PTGS2TAAR1HMGCR | |
| SCHEMBL23326313 | 0.79 | HTR2A (0.66) | HTR2ATAAR1 | |
| SCHEMBL29775337 | 0.79 | HTR2A (0.66) | HTR2ATAAR1 | |
| SCHEMBL7955089 | 0.79 | HTR2A (0.52) | HTR2ATAAR1HMGCR | |
| SCHEMBL14655201 | 0.76 | TAAR1 (0.50) | HTR2AALOX5PTGS2TAAR1HMGCR | |
| SCHEMBL27002092 | 0.76 | TAAR1 (0.70) | HTR2AALOX5PTGS2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204323-A1 | NON-HALLUCINOGENIC ARIADNE ANALOGS FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-09-29 | — | — | WO | disclosed |