Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TRPA1 | O75762 | 8/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249487 | 0.89 | MAPT (1.00) | MAPTSMN1; SMN2LMNATRPA1RXFP1 | |
| SCHEMBL13133516 | 0.89 | MAPT (0.73) | MAPTSMN1; SMN2LMNATRPA1RXFP1 | |
| SCHEMBL23544502 | 0.86 | MAPT (0.72) | MAPTSMN1; SMN2LMNATRPA1RXFP1 | |
| SCHEMBL18166657 | 0.85 | MAPT (0.82) | MAPTSMN1; SMN2LMNATRPA1RXFP1 | |
| SCHEMBL28771520 | 0.84 | MAPT (0.56) | MAPTTRPA1NPC1RAB9APORCN | |
| SCHEMBL28771519 | 0.84 | MAPT (0.56) | MAPTTRPA1NPC1RAB9APORCN | |
| SCHEMBL18166579 | 0.83 | MAPT (0.76) | MAPTSMN1; SMN2LMNATRPA1RXFP1 | |
| SCHEMBL18166721 | 0.83 | MAPT (0.80) | MAPTSMN1; SMN2LMNATRPA1RXFP1 | |
| SCHEMBL10114087 | 0.83 | MAPT (1.00) | MAPTSMN1; SMN2LMNATRPA1RXFP1 | |
| SCHEMBL4540036 | 0.83 | MAPT (0.73) | MAPTSMN1; SMN2LMNATRPA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4105212-A1 | PREPARATION METHOD FOR AND CRYSTAL FORM OF 3-ARYLOXY-3-FIVE-MEMBERED HETEROARYL-PROPYLAMINE COMPOUND | Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd. (CN) | 2022-12-21 | — | — | EP | disclosed |