SCHEMBL2476797

SCHEMBL2476797

O=C(O)c1ccc(C(=O)O)c(Nc2ccccc2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.63
KDM4E B2RXH2 2/20 0.63
ALDH1A1 P00352 1/20 0.63
GAA P10253 1/20 0.63
THRB P10828 1/20 0.63
HPGD P15428 1/20 0.63
HSD17B10 Q99714 1/20 0.63
AKR1C3 P42330 12/20 0.62
AKR1C2 P52895 12/20 0.62
GFER P55789 1/20 0.62
NGLY1 Q96IV0 1/20 0.62
FABP4 P15090 1/20 0.61
AKR1C4 P17516 3/20 0.59
AKR1C1 Q04828 3/20 0.59
AKR1B10 O60218 2/20 0.59
AKR1B1 P15121 2/20 0.59
HCAR3 P49019 1/20 0.56
CXCR2 P25025 1/20 0.51
RHOA P61586 1/20 0.50
CTSV O60911 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29071829 0.90 AKR1C3 (0.72) AKR1C3AKR1C2AKR1C4AKR1C1AKR1B10
SCHEMBL2425054 0.88 MAPT (0.62) MAPTKDM4EALDH1A1GAATHRB
SCHEMBL4640305 0.85 MAPT (0.72) MAPTKDM4EALDH1A1GAATHRB
SCHEMBL3237539 0.85 AKR1C3 (0.67) MAPTKDM4EALDH1A1GAATHRB
SCHEMBL7093800 0.85 AKR1C3 (0.65) MAPTAKR1C3AKR1C2AKR1C4AKR1C1
SCHEMBL31150705 0.84 AKR1C3 (0.69) MAPTKDM4EALDH1A1GAATHRB
SCHEMBL7869107 0.84 AKR1C3 (0.67) KDM4EHPGDAKR1C3AKR1C2GFER
SCHEMBL28968868 0.84 AKR1C3 (0.50) MAPTKDM4EALDH1A1GAATHRB
SCHEMBL7113569 0.84 AKR1C3 (0.57) MAPTKDM4EALDH1A1GAATHRB
SCHEMBL28472949 0.84 AKR1C3 (0.64) MAPTKDM4EALDH1A1GAATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199653-A1 METHOD FOR FORMING AN ELECTRICALLY CONDUCTIVE METAL ORGANIC FRAMEWORK COMPOSITE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-06-20 US claimed
CN-116218167-B Antistatic master batch, antistatic polyester film and preparation method thereof 合肥长阳新材料科技有限公司 2023-07-21 CN claimed
CN-116218167-A Antistatic master batch, antistatic polyester film and preparation method thereof 合肥长阳新材料科技有限公司 2023-06-06 CN claimed
CN-104072403-B A kind of method preparing compound UNC1215 CHENGDU UNIVERSITY (CN) 2016-04-13 CN claimed
US-8968454-B2 Magenta quinacridone pigments CLARIANT FINANCE (BVI) LIMITED (VG) 2015-03-03 US claimed
CN-104072403-A Method for preparing compound UNC1215 UNIV CHENGDU 2014-10-01 CN claimed
EP-2556117-A1 NEW MAGENTA QUINACRIDONE PIGMENTS Clariant Finance (BVI) Limited (VG) 2013-02-13 EP claimed
US-20130029265-A1 New Magenta Quinacridone Pigments CLARIANT FINANCE (BVI) LIMITED (VG) 2013-01-31 US claimed
EP-2374848-B1 New magenta quinacridone pigments CLARIANT FINANCE BVI LTD (VG) 2013-01-16 EP claimed
CN-102762666-A Novel magenta quinacridone pigments CLARIANT INTERNAT BVI LTD 2012-10-31 CN claimed
WO-2011124327-A1 NEW MAGENTA QUINACRIDONE PIGMENTS CLARIANT INTERNATIONAL LTD (CH) 2011-10-13 WO claimed
EP-2374848-A1 New magenta quinacridone pigments Clariant International Ltd. (CH) 2011-10-12 EP claimed
US-4099980-A Process for producing gamma quinacridone solid solutions HARMON COLORS CORPORATION (US) 1978-07-11 US claimed
US-3940399-A Process for the production of gamma quinacridone ALLIED CHEMICAL CORPORATION (US) 1976-02-24 US claimed
US-12516071-B2 Method for forming an electrically conductive metal organic framework composite KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-01-06 US disclosed
US-20250346585-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2025-11-13 US disclosed
CN-116063688-B Flexible metal-organic framework material and preparation method thereof 广东美的白色家电技术创新中心有限公司 2024-07-16 CN disclosed
US-4099980-A Process for producing gamma quinacridone solid solutions HARMON COLORS CORPORATION (US) 1978-07-11 US disclosed
US-3940399-A Process for the production of gamma quinacridone ALLIED CHEMICAL CORPORATION (US) 1976-02-24 US disclosed
US-3940399-A Process for the production of gamma quinacridone ALLIED CHEMICAL CORPORATION (US) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346585-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C5, C1S, C9 MAPT 1464/4885KDM4E 4647/4885ALDH1A1 1707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.