Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 1.00 |
| ▸ | EPHA2 | P29317 | 4/20 | 1.00 |
| ▸ | CASP7 | P55210 | 3/20 | 1.00 |
| ▸ | VDR | P11473 | 3/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | MDM4 | O15151 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | HSPD1 | P10809 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 1/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithocholic Acid SCHEMBL22756077 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7VDRHIF1A | |
| Lithocholic Acid SCHEMBL22894393 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7VDRHIF1A | |
| Lithocholic Acid SCHEMBL22871939 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7VDRHIF1A | |
| Lithocholic Acid SCHEMBL22079173 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7VDRHIF1A | |
| Lithocholic Acid SCHEMBL24001494 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7VDRHIF1A | |
| Lithocholic Acid SCHEMBL22894425 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7VDRHIF1A | |
| Lithocholic Acid SCHEMBL23923735 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7VDRHIF1A | |
| Lithocholic Acid SCHEMBL24001453 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7VDRHIF1A | |
| Lithocholic Acid SCHEMBL24567422 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7VDRHIF1A | |
| Lithocholic Acid SCHEMBL22415871 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7VDRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002526-A1 | PHARMACEUTICAL COMPOSITION HAVING ANTI-CANCER IMMUNOSTIMULATING EFFECT AND/OR IMMUNE CHECKPOINT INHIBITION POTENTIATING EFFECT | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2025-01-02 | — | — | US | claimed |
| EP-0424232-B1 | Process for the production of chenodesoxycholic | SANOFI SA (FR) | 1996-02-21 | — | — | EP | claimed |
| US-4486532-A | IMMOBILIZATION OF FUMARASE-PRODUCING MICROORGANISM | TNANBE SEIYAKU CO., LTD. (JP) | 1984-12-04 | — | — | US | claimed |
| EP-0058000-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1982-08-18 | — | — | EP | claimed |
| JP-58053942-A | — | — | None | — | — | JP | disclosed |
| JP-55153799-A | — | — | None | — | — | JP | disclosed |
| US-20260014089-A1 | METHODS AND COMPOSITIONS FOR DENDRITIC CELL TARGETING NANO-DELIVERY | ROCK BIOMEDICAL INC (TW) | 2026-01-15 | — | — | US | disclosed |
| EP-3472339-B1 | COUPLED BIOTRANSFORMATION OF CHENODEOXYCHOLIC ACID TO URSODEOXYCHOLIC ACID AND ENZYME MUTANTS APPLICABLE IN SAID PROCESS | PHARMAZELL GMBH (DE) | 2020-09-02 | — | — | EP | disclosed |
| US-10246481-B2 | Bile acid derivatives and methods for synthesis and use | CITY OF HOPE (US) | 2019-04-02 | — | — | US | disclosed |
| US-20180319836-A1 | BILE ACID DERIVATIVES AND METHODS FOR SYNTHESIS AND USE | HOPE CITY (US) | 2018-11-08 | — | — | US | disclosed |
| US-20170233431-A1 | BILE ACID DERIVATIVES AND METHODS FOR SYNTHESIS AND USE | HOPE CITY (US) | 2017-08-17 | — | — | US | disclosed |
| EP-1535997-B1 | METHOD OF PURIFYING PROTEIN AND GLUCOSE DEHYDROGENASE | ARKRAY INC (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-0348015-A1 | Hair preparation | Kao Corporation (JP) | 1989-12-27 | — | — | EP | disclosed |
| EP-0295903-A2 | Hair preparation | Kao Corporation (JP) | 1988-12-21 | — | — | EP | disclosed |
| US-4664910-A | ABSORPTION OF EXCESS GREASE OR MOISTURE FROM SKIN OR HAIR | LEVER BROTHERS COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| US-4486532-A | IMMOBILIZATION OF FUMARASE-PRODUCING MICROORGANISM | TNANBE SEIYAKU CO., LTD. (JP) | 1984-12-04 | — | — | US | disclosed |
| US-4460509-A | STEROIDS WITH HETERO RING SIDE CHAIN | BETH ISRAEL MEDICAL CENTER (US) | 1984-07-17 | — | — | US | disclosed |
| JP-S5853942-A | POLYESTER COMPOSITION | NIPPON ESTER CO LTD | 1983-03-30 | — | — | JP | disclosed |
| EP-0058000-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1982-08-18 | — | — | EP | disclosed |
| JP-S55153799-A | PREPARATION OF 3ALPHA-HYDROXY-KETO-CHOLANIC ACID | AMANO PHARMACEUT CO LTD | 1980-11-29 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002526-A1 | PHARMACEUTICAL COMPOSITION HAVING ANTI-CANCER IMMUNOSTIMULATING EFFECT AND/OR IMMUNE CHECKPOINT INHIBITION POTENTIATING EFFECT | CD274, PDCD1, PDCD1LG2 | GPBAR1 2974/4885EPHA2 1399/4885CASP7 651/4885 |
| US-20260014089-A1 | METHODS AND COMPOSITIONS FOR DENDRITIC CELL TARGETING NANO-DELIVERY | CD4, LY6K, CLEC4M | GPBAR1 1871/4885EPHA2 370/4885CASP7 770/4885 |
| US-20170233431-A1 | BILE ACID DERIVATIVES AND METHODS FOR SYNTHESIS AND USE | NR1H4, GPBAR1, SLC10A1 | GPBAR1 2/4885EPHA2 236/4885CASP7 3756/4885 |
| US-10246481-B2 | Bile acid derivatives and methods for synthesis and use | NR1H4, GPBAR1, SLC10A1 | GPBAR1 2/4885EPHA2 236/4885CASP7 3756/4885 |
| US-20180319836-A1 | BILE ACID DERIVATIVES AND METHODS FOR SYNTHESIS AND USE | NR1H4, GPBAR1, SLC10A1 | GPBAR1 2/4885EPHA2 236/4885CASP7 3756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.