Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 11/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.82 |
| ▸ | HTT | P42858 | 4/20 | 0.82 |
| ▸ | LMNA | P02545 | 4/20 | 0.82 |
| ▸ | TP53 | P04637 | 2/20 | 0.82 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31575397 | 0.97 | PCSK9 (0.94) | PCSK9SMN1; SMN2HTTLMNATP53 | |
| SCHEMBL24770688 | 0.90 | PCSK9 (0.82) | PCSK9SMN1; SMN2HTTLMNATP53 | |
| SCHEMBL12604460 | 0.89 | PCSK9 (1.00) | PCSK9SMN1; SMN2HTTLMNATP53 | |
| SCHEMBL31575436 | 0.87 | PCSK9 (0.88) | PCSK9SMN1; SMN2HTTLMNATP53 | |
| SCHEMBL24770696 | 0.87 | PCSK9 (0.80) | PCSK9SMN1; SMN2HTTLMNATP53 | |
| SCHEMBL19560465 | 0.86 | HTT (0.76) | PCSK9SMN1; SMN2HTTLMNATP53 | |
| SCHEMBL31159628 | 0.86 | PCSK9 (0.80) | PCSK9SMN1; SMN2HTTLMNATP53 | |
| SCHEMBL31575437 | 0.85 | PCSK9 (0.83) | PCSK9SMN1; SMN2HTTLMNATP53 | |
| SCHEMBL31575411 | 0.85 | PCSK9 (0.73) | PCSK9SMN1; SMN2HTTLMNATP53 | |
| SCHEMBL31575429 | 0.85 | PCSK9 (0.73) | PCSK9SMN1; SMN2HTTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262820-A1 | GROUP OF IMB-C5 SERIES COMPOUNDS HAVING ANTI-CORONAVIRUS ACTIVITY AND APPLICATION THEREOF | 中国医学科学院医药生物技术研究所 | 2022-12-22 | — | — | WO | disclosed |