Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31032114 | 1.00 | POLQ (1.00) | POLQ | |
| SCHEMBL24769188 | 0.87 | POLQ (0.84) | POLQ | |
| SCHEMBL30017162 | 0.87 | POLQ (0.84) | POLQ | |
| SCHEMBL24770341 | 0.86 | POLQ (0.80) | POLQ | |
| SCHEMBL31032059 | 0.86 | POLQ (0.80) | POLQ | |
| SCHEMBL24769157 | 0.84 | POLQ (0.73) | POLQ | |
| SCHEMBL24769963 | 0.84 | POLQ (0.83) | POLQ | |
| SCHEMBL24769699 | 0.84 | POLQ (0.77) | POLQ | |
| SCHEMBL24769358 | 0.84 | POLQ (1.00) | POLQ | |
| SCHEMBL30016187 | 0.84 | POLQ (0.77) | POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022259204-A1 | O-LINKED THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2022-12-15 | — | — | WO | disclosed |