Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24500339 | 0.89 | POLQ (0.61) | POLQ | |
| SCHEMBL30640125 | 0.89 | POLQ (0.61) | POLQ | |
| SCHEMBL24769580 | 0.88 | POLQ (0.60) | POLQ | |
| SCHEMBL24770165 | 0.85 | POLQ (0.53) | POLQ | |
| SCHEMBL30017601 | 0.84 | POLQ (0.64) | POLQTDP1 | |
| SCHEMBL24770230 | 0.84 | POLQ (0.64) | POLQTDP1 | |
| SCHEMBL30858982 | 0.84 | POLQ (0.54) | POLQ | |
| SCHEMBL30640105 | 0.83 | POLQ (0.48) | POLQ | |
| SCHEMBL24769264 | 0.83 | POLQ (0.48) | POLQ | |
| SCHEMBL24770191 | 0.83 | POLQ (0.50) | POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4352055-A1 | O-LINKED THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS | Ideaya Biosciences, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022259204-A1 | O-LINKED THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| WO-2022259204-A1 | O-LINKED THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2022-12-15 | — | — | WO | disclosed |