Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 15/20 | 0.52 |
| ▸ | FEN1 | P39748 | 14/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30680160 | 1.00 | ALOX5AP (0.52) | ALOX5APFEN1KITADORA1ADORA2A | |
| SCHEMBL30680194 | 0.90 | ALOX5AP (0.58) | ALOX5APFEN1KITADORA1ADORA2A | |
| SCHEMBL29126846 | 0.90 | ALOX5AP (0.58) | ALOX5APFEN1KITADORA1ADORA2A | |
| SCHEMBL24772716 | 0.89 | ALOX5AP (0.52) | ALOX5APFEN1KITADORA1CYP3A4 | |
| SCHEMBL24773647 | 0.89 | ALOX5AP (0.49) | ALOX5APFEN1ADORA1ADORA2ACYP3A4 | |
| SCHEMBL30680176 | 0.85 | ALOX5AP (0.52) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL30680159 | 0.85 | ALOX5AP (0.44) | ALOX5APFEN1ADORA1ADORA2A | |
| SCHEMBL29126858 | 0.85 | ALOX5AP (0.44) | ALOX5APFEN1ADORA1ADORA2A | |
| SCHEMBL24773007 | 0.82 | ALOX5AP (0.53) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL24773325 | 0.80 | ALOX5AP (0.44) | ALOX5APFEN1KITCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206939-A1 | HETEROCYCLIC COMPOUND SERVING AS FGFR INHIBITOR AND APPLICATION THEREOF | 海南耀臻生物医药科技有限公司 | 2022-10-06 | — | — | WO | disclosed |