Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477344 | 0.78 | SLC6A4 (0.32) | SLC6A4 | |
| SCHEMBL2478239 | 0.70 | SLC6A4 (0.33) | SLC6A4 | |
| SCHEMBL20158436 | 0.64 | SLC6A4 (0.55) | SLC6A4 | |
| SCHEMBL9683909 | 0.64 | SLC6A4 (0.40) | SLC6A4 | |
| SCHEMBL20012540 | 0.62 | CARM1 (0.47) | SLC6A4 | |
| SCHEMBL22857078 | 0.62 | SLC6A4 (0.42) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL9682487 | 0.62 | SLC6A4 (0.39) | SLC6A4 | |
| SCHEMBL6309381 | 0.61 | HRH3 (0.47) | SLC6A4 | |
| SCHEMBL20147951 | 0.60 | PDE9A (0.35) | SLC6A4 | |
| SCHEMBL13940565 | 0.60 | GRIN1 (0.46) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376494-A1 | DIHYDROPYRIMIDOPYRIMIDINE DERIVATIVES | MSD K.K. (JP) | 2011-10-19 | — | — | EP | disclosed |
| EP-2376493-A1 | DIHYDROPYRIMIDOPYRIMIDINE DERIVATIVE | MSD K.K. (JP) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010067886-A1 | DIHYDROPYRIMIDOPYRIMIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-06-17 | — | — | WO | disclosed |
| WO-2010067888-A1 | DIHYDROPYRIMIDOPYRIMIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-06-17 | — | — | WO | disclosed |