Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25772761 | 0.87 | TSHR (0.50) | TSHRCYP2D6SMN1; SMN2 | |
| SCHEMBL1710042 | 0.80 | KDM4E (0.37) | TSHRCYP2D6SMN1; SMN2KDM4EGAA | |
| SCHEMBL24235262 | 0.80 | CYP2D6 (0.55) | TSHRCYP2D6SMN1; SMN2 | |
| SCHEMBL23559996 | 0.80 | TSHR (0.48) | TSHRCYP2D6SMN1; SMN2KDM4EGAA | |
| SCHEMBL6923193 | 0.78 | TSHR (0.47) | TSHRCYP2D6SMN1; SMN2KDM4EGAA | |
| SCHEMBL26501920 | 0.76 | TSHR (0.34) | TSHR | |
| SCHEMBL21106257 | 0.76 | CYP2D6 (0.59) | TSHRCYP2D6SMN1; SMN2 | |
| SCHEMBL27281812 | 0.75 | CYP2D6 (0.46) | TSHRCYP2D6SMN1; SMN2 | |
| SCHEMBL25772888 | 0.75 | TSHR (0.36) | TSHRKDM4EOPRM1 | |
| SCHEMBL21216356 | 0.74 | KDM4E (0.34) | TSHRSMN1; SMN2KDM4EGAAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4104861-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2022-12-21 | — | — | EP | disclosed |